PFKFB3 抗体
Quick Overview for PFKFB3 抗体 (ABIN7674357)
抗原
See all PFKFB3 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- PFKFB3-Specific antibody
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纯化方法
- Immunogen affinity purified
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纯度
- ≥95 % as determined by SDS-PAGE
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免疫原
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
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亚型
- IgG
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应用备注
- WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze / thaw cycles.
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储存条件
- -20 °C
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储存方法
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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有效期
- 12 months
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- PFKFB3 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 3 (PFKFB3))
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别名
- PFKFB3
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背景
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Synonyms: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3, PFK/FBPase 3)|6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme|Renal carcinoma antigen NY-REN-56|iPFK-2|PFKFB3
Background: PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.
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分子量
- 58 kDa
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基因ID
- 5209
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UniProt
- Q16875
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途径
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process
抗原
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